Past studies

2005

Nine studies in cardiology or cardiothoracic surgery involving:
Thomas Davis, MD
M. Mark Melin, MD
Jeffrey Mendeloff, MD
Steven Santilli, MD
Jay Simonson, MD
Ted Spooner, MD
John Thomas Suh, MD
Jackson Thatcher, MD

• Observations on the Effect of a Perioperative Beta-Blockade Protocol on Reducing Cardiovascular Complications in Surgery Patients Treated in a Community Hospital Setting.
  Principal Investigator: Jackson Thatcher, MD
  Sponsor: Park Nicollet Health Services
• Artery Wall Hypoxia and Intimal Hyperplasia
  Local Principal Investigators:
  Steven Santilli, MD, and Jeffrey Mendeloff, MD
  Sponsor: National Institutes of Health

2004 

Four cardiology studies; one cardiothoracic surgery study

2003

• Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Long-Term Efficacy and Safety of a Study Drug in Subjects Hospitalized with Worsening Congestive Heart Failure
  Principal Investigator: Thomas Suh, MD
  Sponsor: Otsuka Maryland Research Institute Inc.
• A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Pilot Study Evaluating the Efficacy and Safety of a Study Drug in Patients with Decompensated Chronic Heart Failure
  Principal Investigator: Thomas Suh, MD
  Sponsor: Yamanouchi Pharma America Inc.
• Registry of Cardiac Resynchronization Therapy-US (RESTORE-US)
  Sponsor: Medtronic Inc.
• A Double-Blind, Randomized, Multicenter, Dose-Ranging Trial of a Study Drug Compared with Clopidogrel in Subjects Undergoing Percutaneous Coronary Intervention (JUMBO-TIMI 26)
  Principal Investigator: J. Mark Haugland, MD
  Sponsor: Eli Lilly and Company
• Efficacy and Safety of a New Oral Direct Thrombin Inhibitor Compared with Dose Adjusted Warfarin (Coumadin) in the Prevention of Stroke and Systemic Embolic Events in Patients with Atrial Fibrillation (SPORTIF V)
  Principal Investigator: J. Mark Haugland, MD
  Sponsor: AstraZeneca
• A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of a Study Drug-Device Combination in the Treatment of Coronary Vein Grafts in Patients Undergoing Coronary Artery Bypass Graft Procedures
  Principal Investigator: Ted Spooner, MD
  Sponsor: Corgentech
• A Comparative, Prospective, Randomized, Double-Masked, Parallel Group, Controlled Trial of a Study Therapy Versus Sham Control When Added to Standard Care in the Treatment of Diabetic Neuropathic Ulcers
  Principal Investigator: M. Mark Melin, MD
  Sponsor: Celleration

2002

• Efficacy and Safety of a New Oral Direct Thrombin Inhibitor Compared with Dose Adjusted Warfarin (Coumadin) in the Prevention of Stroke and Systemic Embolic Events in Patients with Atrial Fibrillation (SPORTIF V)
  Principal Investigator: J. Mark Haugland, MD
  Sponsor: AstraZeneca
• Pravastatin or Atorvastatin Evaluation and Infectious Therapy (PROVE IT)
  Principal Investigator: Gary Cramer, MD
  Sponsor: Bristol-Myers Squibb Company
• Pain Free Rx II (Does PacINg Fast VT ReducE Shock Rx?)
  Principal Investigator: Wayne Adkisson, MD
  Sponsor: Medtronic Inc.
• Primary Angioplasty with Tirofiban in a Community Hospital (PATCH) Methodist Hospital Study of Major Adverse Events (MACE) in Tirofiban-Assisted Primary Angioplasty for Acute Myocardial Infarction
  Principal Investigator: Jackson Thatcher, MD
  Sponsor: Merck & Co. Inc.
• Monitoring the Troponin Complex, Brain Natiuretic Peptide, and C-Reactive Protein in Patients with Congestive Heart Failure: Longitudinal Follow-up and Relationship to Length of Stay
  Principal Investigator: John Thomas Suh, MD
  Sponsor: Park Nicollet Institute
• Cardiothoracic Surgery, A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of a New Drug-Device Combination in the Treatment of Coronary Vein Grafts in Patients Undergoing Coronary Artery Bypass Graft Procedures
  Principal Investigator: Ted Spooner, MD
  Sponsor: Corgentech
  2001
• Efficacy and Safety of a new Oral Direct Thrombin Inhibitor Compared with Dose Adjusted Warfarin (Coumadin) in the Prevention of Stroke and Systemic Embolic Events in Patients with Atrial Fibrillation (SPORTIF V)
  Principal Investigator: J. Mark Haugland, MD
  Sponsor: AstraZeneca
• Pravastatin or Atorvastatin Evaluation and Infectious Therapy (PROVE IT)
  Principal Investigator: Gary Cramer, MD
  Sponsor: Bristol-Myers Squibb Company
• Feasibility and Accuracy of Stress Echo Using Myocardial Contrast Echocardiography (MCE): Comparison with Scintigraphy and Wall Motion Analysis
  Principal Investigator: Richard Madlon-Kay, MD
  Sponsor: Park Nicollet Institute
• Pain Free Rx II (Does PacINg Fast VT ReducE Shock Rx?)
  Principal Investigator: Wayne Adkisson, MD
  Sponsor: Medtronic Inc.
• Evaluation of Cardiac Sounds Using the 3M™ Littmann® Electronic Stethoscope Model 4000
  Principal Investigator: Thomas Davis, MD
  Sponsor: 3M Pharmaceuticals
• Primary Angioplasty with Tirofiban in a Community Hospital (PATCH) Methodist Hospital Study of Major Adverse Events (MACE) in Tirofiban-Assisted Primary Angioplasty for Acute Myocardial Infarction
  Principal Investigator: Jackson Thatcher, MD
  Sponsor: Merck & Co. Inc.
• Assessing Syncope Using Reveal (Assure®)
  Principal Investigator: Wayne Adkisson, MD
  Sponsor: Outcome Sciences

• A Randomized, Controlled, Multicenter Trial of Vacuum Assisted Closure Therapy with Split-Thickness Skin Grafting in the Treatment and Blinded Evaluation of Venous Stasis Ulcers
   Principal Investigator: Mark Melin, MD
   Sponsor: Kinetic Concepts Inc.

• A Randomized, Controlled, Multicenter Trial of Vacuum Assisted Closure Therapy in the Treatment and Blinded Evaluation of Venous Stasis Ulcers
  Principal Investigator: Mark Melin, MD
  Sponsor: Kinetic Concepts Inc.