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2005 Institute Annual Report 2005 Institute Annual Report
2005 Institute Annual Report > Research Studies

Research studies

Researchers from across Park Nicollet Health Services participated in 225 studies in 2005, investigating a wide range of topics and activities. To review a list of all of the generous sponsors of our research studies, see the left navigation bar. Sponsors of our investigator-initiated and federally or nationally funded studies are noted here. Principal investigators are Park Nicollet employees unless otherwise noted.

Asthma and Allergy, 13 active studies

Principal investigators
David Graft, MD
Pamela Harris, MD
William Schoenwetter, MD
Richard Sveum, MD
Richard Wyatt, MD

Cardiology, 6 active studies

Principal investigators
Thomas Davis, MD
Jay Simonson, MD
John Thomas Suh, MD
Jackson Thatcher, MD

Investigator-initiated research

Observations on the Effect of a Perioperative Beta-Blockade Protocol on Reducing Cardiovascular Complications in Surgery Patients Treated in a Community Hospital Setting
Principal Investigator: Jackson Thatcher, MD
Sponsor: Park Nicollet Health Services

Cardiothoracic Surgery, 1 active study

Principal investigator
Ted Spooner, MD

Ear, Nose and Throat, 1 active study

Principal investigator
Katherine Kendall, MD

Investigator-initiated research

High-Speed Laryngeal Imaging: Normal Physiology
Principal investigator: Katherine Kendall, MD
Sponsor: Park Nicollet Institute

Eating Disorders Institute, 10 active studies

Principal investigators
Diann Ackard, PhD, LP
Jillian Croll, PhD, RD, MPH
Scott Crow, MD
Elke Eckert, MD, University of Minnesota
Annie Heiderscheit
Helene Keery, PhD, LP
Betty Schmidt, RN
Robyn Swenson, PhD, LP

Investigator-initiated research

Anna Westin House Residential Outcomes Study
Principal investigator: Jillian Croll, PhD, RD, MPH
Sponsor: Blue Cross Blue Shield of Minnesota Foundation

Do Female Patients Identifying Themselves as Athletes Differ Clinically from Non-Athlete Females Presenting for Eating Disorder Treatment?
Principal investigator: Robyn Swenson, PhD, LP
Sponsor: Park Nicollet Foundation

A Comparison of the Impact of Appearance-Related Teasing on Adolescents Seeking Treatment for an Eating Disorder and a Community Sample of Adolescents
Principal investigator: Helene Keery, PhD, LP
Sponsor: Park Nicollet Foundation

Do Eating Disorder Patients Experiencing an Early Onset (10-12 years of age) Differ Clinically from Patients Whose Onset Occurs During Adolescence or Young Adulthood?
Principal investigator: Robyn Swenson, PhD, LP
Sponsor: Park Nicollet Institute

A Ten-Year Follow-Up Study Examining Cross-Cultural Differences between High-School Aged African American, Caucasian American, Bahamian and Namibian Males and Females with Regard to Body Dissatisfaction and Other Eating Disorder Risks
Principal investigator: Robyn Swenson, PhD, LP
Sponsor: Park Nicollet Institute

Stage of Change as a Predictor of Treatment Outcome among Individuals Seeking Treatment for an Eating Disorder
Principal Investigator: Diann Ackard, PhD, LP
Sponsor: Park Nicollet Foundation

The Effectiveness of Music Listening for Managing Stress and Anxiety for Eating Disorder Patients during Mealtime
Principal Investigator: Annie Heiderscheit
Sponsor: Park Nicollet Foundation

Pattern Recognition with Women in Recovery from an Eating Disorder
Principal Investigator: Betty Schmidt, MS, RN, CRRN, HNC
Sponsor: Park Nicollet Foundation

Family Medicine, 2 active studies

Principal investigators
Don Pine, MD
John Robrock, MD

Investigator-initiated research

Development of a Clinician Referral Intervention to Tobacco Quitlines
Principal investigator: Don Pine, MD
Sponsor: Park Nicollet Foundation

Health Information Management, 3 active studies

Principal investigators
Catherine Borbas, PhD, MPH, Healthcare Education and Research Foundation
Aaron Folsom, MD, University of Minnesota
Eyal Sharer, MD, PhD, University of Minnesota

Health Research Center, 17 active studies

Principal investigators
Renner Anderson, MD
Mary Sue Beran, MD, MPH
Barbara Braun, PhD
Jinnet Fowles, PhD
Peter Harper, MD, HealthPartners Research Foundation
Margaret Healey, PhD
David Homans, MD
Allan Kind, MD
Elizabeth Kind, MS, RN
David Knutson
Sharon Rolnick, PhD, HealthPartners Research Foundation
Feifei Wei, PhD, HealthPartners Research Foundation

Investigator-initiated research

A Randomized, Placebo-Controlled Study of the Effectiveness of Dietary Phyosterols to Lower Cholesterol in Employees Who are Enrolled in a Worksite Health Promotion Program
Principal Investigator: Margaret Healey, PhD
Sponsor: Cargill

Weight Management, Physical Activity, Less Disability in Rheumatoid and Osteoarthritis
Principal Investigator: Barbara Braun, PhD
Sponsor: Centers for Disease Control and Prevention

Impact of Secure Messaging on the COMPASS Program
Principal Investigators: Allan Kind, MD, and Jinnet Fowles, PhD
Sponsor: Tonkawa Inc.

Women’s Perception of Cardiovascular Disease Risk
Principal Investigator: David Homans, MD
Sponsor: Park Nicollet Institute

An Investigation of the Uses of Health-Based Risk Adjustment by Purchasers and Health Plans
Principal Investigator: David Knutson
Sponsor: The Robert Wood Johnson Foundation’s Program in Changes in Health Care Financing and Organization

Patient On-Line Evaluation
Principal Investigator: Allan Kind, MD
Sponsor: Curtis L. Carlson Family Foundation

Survey of Needs for and Uses of Community Services by Older Adults Who Live in St. Louis Park: Evaluation of the Nurturing Our Retired Citizens (NORC) Project
Principal Investigator: Elizabeth Kind, MS, RN
Sponsor: Administration on Aging, Health and Human Services

Physician Communication with Obese Patients
Principal Investigator: Mary Sue Beran, MD, MPH
Sponsor: Park Nicollet Foundation

Comprehensive Visit Planning for Medicaid Managed Care Patients (MMCP)
Principal Investigator: Barbara Braun, PhD
Sponsor: Center for Health Care Strategies

Patient Perspective on Alternative Disease Management Approaches
Principal Investigator: Jinnet Fowles, PhD
Sponsor: Park Nicollet Foundation

Patient On-Line Evaluation–Cardiology
Principal Investigator: Allan Kind, MD
Sponsor: Park Nicollet Health Services

E-Indicators of Health Care Provider Performance:  Developing, Evaluating, and Implementing Electronic Health Record-Based Quality Indicators for Ambulatory and Integrated Health Care Systems
Principal Investigator: Jinnet Fowles, PhD
Sponsor: Commonwealth Fund and Robert Wood Johnson Foundation

Federally or nationally funded multicenter studies

Vaccine Safety Data Link Project
Principal investigator: Michael Goodman, PhD, HealthPartners Foundation
Local principal investigator: Renner Anderson, MD
Sponsor: Centers for Disease Control and Prevention

Park Nicollet HealthSource, 4 active studies

Principal investigators
Kris Haugen
Mary Kruse
Paul Terry, PhD
Ted Wegleitner

Investigator-initiated research

Healthy Young Workers Project: A Demonstration Project to Implement and Evaluate Promising Policy Change Initiatives with 18-24 Year-Olds
Principal investigator: Ted Wegleitner
Sponsor: Minnesota Partnership for Action Against Tobacco

Standard Worksite Health Program Versus Activated Consumer
Principal investigator: Paul Terry, PhD
Sponsor: Centers for Disease Control and Prevention

Improving Physical Activity and Preventing Relapse in a Health Care Employee Population
Pincipal investigator: Mary Kruse
Sponsor: Park Nicollet Foundation

Evaluation of the Park Nicollet Employee Health Promotion Program
Principal investigator: Kris Haugen
Sponsor: Park Nicollet Health Services

Infectious Disease, 3 active studies

Principal investigator
Harold Martin, MD

Federally or nationally funded multicenter studies

Study to Understand the Natural History of HIV and AIDS in the Era of Effective Therapy (SUN)
Local principal investigator: Harold Martin, MD
Sponsor: Centers for Disease Control and Prevention

Internal Medicine, 1 active study

Principal investigator
Anthony Woolley, MD

International Diabetes Center, 50 active studies

Principal investigators
Richard Bergenstal, MD
Amy Criego, MD
Gregory Damberg, MD
Lisa Fish, MD
David Kendall, MD
Roger Mazze, PhD
William Richards, MD
Martha Spencer, MD
Lorraine Schafer, PhD

Investigator-initiated research

Worksite Diabetes Management: Partnering for Success
Principal Investigator: Richard Bergenstal, MD
Sponsor: Park Nicollet Foundation

Intensive Care Unit Glucose Control Study 
Principal Investigator: Lisa Fish, MD
Sponsor: Park Nicollet Foundation

Partners in Advancing Care and Education Solutions
Principal Investigator: Roger Mazze, PhD
Sponsor: Novartis Pharmaceuticals Corporation

Diabetes Coaching at the Worksite
Principal Investigator: Lorraine Schafer, PhD
Sponsor: Park Nicollet Foundation and Park Nicollet Institute

Lions Diabetes of Minnesota Project
Principal Investigator: Roger Mazze, PhD
Sponsor: Lions of Minnesota

Federally or nationally funded multicenter studies

Driving Safety and Diabetes
Principal investigator: Roger Mazze, PhD
Sponsor: National Institutes of Health

Central Obesity and Elevated Albumin Excretion in Type 1 Diabetes
Local Principal Investigator: Richard Bergenstal, MD
Sponsor: National Institutes of Health

Genetic Studies of Diabetic Complications in Epidemiology of Diabetes Interventions and Complications
Local Principal Investigator: Richard Bergenstal, MD
Sponsor: National Institutes of Health

Action to Control Cardiovascular Risk in Diabetes (ACCORD) and Action to Control Cardiovascular Risk in Diabetes:
• Memory in Diabetes Substudy
• Ancillary Eye Study
Local Principal Investigators: Richard Bergenstal, MD and David Kendall, MD
Sponsor: National Institutes of Health

Does Treatment Affect Cognition in Type 1 Diabetes?
Local Principal Investigator: Richard Bergenstal, MD
Sponsor: National Institutes of Health

The DREAM (Diabetes Reduction Assessment with Ramipril and Rosiglitazone Medication) Trial
Local Principal Investigator: Richard Bergenstal, MD
Sponsors: Canadian Institutes of Health Research, Aventis Pharmaceuticals, King Pharmaceuticals and GlaxoSmithKline

Neurology, 13 active studies

Principal investigators
Sandra Hanson, MD
Frederick Taylor, MD

Federally or nationally funded multicenter studies

Carotid Occlusion Surgery Study
Local principal investigator: Sandra Hanson, MD
Sponsor: National Institute of Neurological Disorders and Stroke

Nursing Administration, 3 active studies

Principal investigators
Barbara Mark, PhD, University of North Carolina
Kristine Peterson, RN, MS, CCRN

Investigator-initiated research

Incontinence Management and Perineal Skin Care in Acutely Ill Patients: Nurses’ Knowledge and Practices
Principal investigator: Kristine Peterson, RN, MS, CCRN
Sponsor: Park Nicollet Institute

Federally or nationally funded multicenter studies

Development of an Evidence-Based Protocol for Prevention of Perineal Dermatitis In Hospitalized Adults with Incontinence
Principal investigator: Kristine Peterson, RN, MS, CCRN
Sponsor: American Association of Critical Care Nurses

Obstetrics and Gynecology, 4 active studies

Principal investigators
Susan Feron, MD, University of Minnesota
Michael Valley, MD

Occupational Medicine/Park Nicollet HealthSource, 1 active study

Principal investigator
David Parker, MD

Investigator-initiated research

Effectiveness of a Machine Guarding Intervention
Principal investigator: David Parker, MD
Sponsor: Centers for Disease Control and Prevention

Oncology Research, 43 active studies

Principal investigators
Peter Argenta, MD
Rachel Ghebre, MD
Keith Heaton, MD
Robin Lally, RN, AOCN, CNS
Martin Lee, MD
Mary Jo Nissen, PhD, MPH
Julie Ross, MD
Alice Shapiro, PhD, RD, LN
Karen Swenson, RN, MS, AOCN
Todd Tuttle, MD
Gretchen Zunkel, PhD, RN

Investigator-initiated research

Predictors of Lymphedema Following Breast Cancer Surgery Principal Investigator: Karen Swenson, RN, MS
Sponsor: U.S. Army Medical Research

Dietary Intake in Women with Breast Cancer: Study 1: Comparison to National Data Sets; Study 2: Predictors to Adherence to a Low-Fat Diet Intervention
Principal Investigator: Alice Shapiro, PhD, RD, LN
Sponsor: Park Nicollet Institute

Breast Cancer Adjuvant Educational Program (BCAEP): A Randomized Clinical Trial of a Computer-Based Learning Tool to Aid in Decision-Making Concerning Adjuvant Therapy for Early Breast Cancer
Principal Investigator: Martin Lee, MD
Sponsor: Park Nicollet Institute

A Study to Evaluate the Axillary Recurrence Rate Following Sentinel Lymph Node Dissection for Breast Cancer
Principal Investigator: Karen Swenson, RN, MS
Sponsor: Park Nicollet Institute

Continuity of Care for Cancer Survivors
Principal Investigator: Mary Jo Nissen, PhD, MPH
Sponsor: Park Nicollet Foundation

Patterns of Care for Cancer Survivors
Principal Investigator: Mary Jo Nissen, PhD, MPH
Sponsor: Park Nicollet Institute

Federally or nationally funded multicenter studies

A Prognostic Study of Sentinel Node and Bone Marrow Micrometastases in Women with Clinical Stage T1 or T2 Breast Cancer
Local principal investigator: Keith Heaton, MD
Sponsor: American College of Surgeons

A Randomized Trial of Axillary Node Dissection in Women With Clinical Stage T1 or T2 N0M Breast Cancer Who Have a Positive Sentinel Node
Local Principal Investigator: Keith Heaton, MD
Sponsor: American College of Surgeons

A Multicenter Clinical Trial to Determine the Efficacy of a Dietary Fat Reduction Program Provided in Addition to Systemic Adjuvant Therapy in the Management of Patients with Primary Invasive Breast Cancer
Local Principal Investigator: Alice Shapiro, PhD
Sponsor: American Health Foundation

University of Minnesota Women’s Cancer Center Protocol #31: A Randomized Study of Two Different Study Drug Combinations for the Treatment of Epithelial Ovarian Cancer in Women Who Have Been Previously Treated
Local Principal Investigator: Martin Lee, MD
Sponsor: University of Minnesota

Orthopedics including TRIA Orthopaedic Center, 6 active studies

Principal investigators
Joel Boyd, MD
William Ford, MD
Carolos Guanche, MD
Allan Hunt, MD
Benjamin Levine, MD

Pathology, 1 active study

Principal investigator
Susan Bowers, MD

Pediatric Endocrinology, 2 active studies

Principal investigators
Michael Ainslie, MD
Martha Spencer, MD

Pediatrics, 1 active study

Principal investigator
Andrew Rzepka, MD

Rheumatology Research Center, 15 active studies

Principal investigators
Peter Kent, MD
Tawatchai Paisansinsup, MD
Eric Schned, MD
John Schousboe, MD
Robert Tierney, MD

Internally generated research

Medication Beliefs and Representations: Scaling and Measurement Properties of a Medications Beliefs Scale
Principal Investigator: John Schousboe, MD
Sponsor: Park Nicollet Institute

Federally or nationally funded multicenter studies

BioMarkers for Anti-TNF Response in Rheumatoid Arthritis
Local Principal Investigator: Eric Schned, MD
Sponsor: National Institutes of Health

Treatment of Early Aggressive Rheumatoid Arthritis (TEAR) Trial
Local principal investigator: Robert Tierney, MD
Sponsor: Rheumatoid Arthritis Investigational Network

The Genetics of Rheumatoid Arthritis (NARAC II)
Local principal investigator: Robert Tierney, MD
Sponsor: Rheumatoid Arthritis Investigational Network

Sexual Health, 2 active studies

Principal investigator
William Borkon, MD

Struthers Parkinson's Center, 20 active studies

Principal investigators
Martha Nance, MD
Sotirios Parashos, MD
Catherine Wielinski, MPH

Internally generated research

Plasma Half-Life of Levodopa after Administration of Additional Carbidopa in Parkinson’s Disease Patients Already Treated with a Combination of Carbidopa/Levodopa and Entacapone
Principal Investigator: Sotirios Parashos, MD
Sponsor: Struthers Parkinson’s Center

Young Onset Parkinson’s Disease Survey
Principal Investigator:  Catherine Wielinski, MPH
Sponsor: Struthers Parkinson’s Center

Cognitive Dysfunction in Parkinson’s Disease, with and without Dementia: Evaluation Using the Cognitive Linguistic Quick Test
Principal Investigator: Sotirios Parashos, MD
Sponsor: Struthers Parkinson’s Center

Validation of the Cognitive Performance Test in Parkinson’s Disease
Principal Investigator: Catherine Wielinski, MPH
Sponsor: Struthers Parkinson’s Center

Physical Therapy Assessments in Parkinson's Disease
Principal Investigator: Catherine Wielinski, MPH
Sponsor: Struthers Parkinson’s Center

Young Onset Parkinson’s Disease Survey: Sexuality and Intimacy
Principal Investigator: Catherine Wielinski, MPH
Sponsor: Struthers Parkinson’s Center

Urology, 1 active study

Principal investigator
William Borkon, MD

Vascular Surgery, 2 active studies

Principal investigators
M. Mark Melin, MD
Jeffrey Mendeloff, MD
Steven Santilli, MD

Federally or nationally funded multicenter studies

Artery Wall Hypoxia and Intimal Hyperplasia
Local Principal Investigators: Steven Santilli, MD, and Jeffrey Mendeloff, MD
Sponsor: National Institutes of Health

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Celebrating the support and collaboration of those who generously contribute to research and education:

    • Sponsors
    • Donors

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