Dylan Zylla - M.D., M.S.

Dylan Zylla - M.D., M.S.

Make an Appointment

To request an appointment online,
log into MyChart.
My Areas of Practice

As a medical oncologist and hematologist, I value the relationships I develop with patients who have cancer or blood disorders.  I strive to provide clear explanations of complex and often frightening diagnoses and support both patients and their families with the compassion they deserve.  My goal is to provide quality, evidence-based medicine that maximizes the opportunity to combat disease, while also preserving one's quality of life. My research interest is to determine how the control of cancer pain may improve clinical outcomes, specifically in patients with cancer of the breast, lung, prostate and colon. I utilize skills from my Masters in Clinical Research to coordinate clinical trials that I hope will improve patient care, relieve suffering, and help advance our understanding of cancer.

General Information

Gender: Male

Practicing Since: 2012

Accepting New Patients: Yes


Practices at

Frauenshuh Cancer Center
3931 Louisiana Ave. S.

Ground and 1st Floors
St. Louis Park, MN 55426

Education & Certifications

Masters in Clinical Research: University of Minnesota
School of Public Health
Minneapolis, MN

Certification: American Board of Internal Medicine
Medical Oncology

Certification: American Board of Internal Medicine

Fellowship: University of Minnesota
Minneapolis, MN

Chief Residency: University of Minnesota - Minneapolis VA Hospital
Internal Medicine
Minneapolis, MN

Certification: American Board of Internal Medicine
Internal Medicine

Residency : University of Minnesota
Minneapolis, MN

M.D.: University of Minnesota
Minneapolis, MN

B.A.: Miami University
Oxford, OH

Research & Publications

My research interests focus on cancer pain, opioid medications, and how each may affect clinical outcomes in patients with advanced cancers. As co-medical director of our oncology research program, I coordinate many of the clinical trials available to our patients at the Frauenshuh Cancer Center. In 2017, I began leading a workgroup to study the impact of medical cannabis on controlling symptoms. Goals of my ongoing projects include: 1) improving pain and nausea with medical cannabis, 2) decreasing complications from high blood sugars in our patients with diabetes, and 3) increasing electronic collection of symptoms between chemotherapy visits.

Zylla, D et al. Establishing personalized pain goals in oncology patients to improve care and decrease costs. J Oncology Practice. 2017; Mar 13(3). 

Zylla, D et al. A systematic review of the impact of pain on overall survival in patients with cancer. Support Care Cancer. 2017; May 25(5).

Zylla, D et al. Impact of opioid use on survival in patients with newly diagnosed stage IV non-hematologic malignancies. J Clin Oncol.  2015; 33 (Suppl 29S, abstract 188).

Zylla, D et al. Pain score, analgesic utilization, and patient satisfaction among cancer patients at a community cancer center. J Clin Oncol. 2014; 32 (Suppl 31, abstract 203). 

Zylla, D et al. Association of opioid requirement and cancer pain with survival in patients with advanced non-small cell lung cancer. British Journal of Anaesthesia.  2014; Oct 10.

Zylla, D, et al. Opioid requirement, opioid receptor expression, and clinical outcomes in patients with advanced prostate cancer. Cancer. 2013 Dec 1; 119 (23)

Zadroga RJ, Zylla D, et al. Pneumoccocal Pyomyositis: Report of two cases and a review of the literature. Clin Infect Dis. 2012 Apr 20.

Lederle, F, Zylla, D, et al. Venous thromboembolism prophylaxis in hospitalized medical and stroke patients: a systematic review for a Clinical Practice Guideline. Annals of Internal Medicine. 2011 Nov 1;155(9):602-15.

Zylla D, Li Y, Bergenstal E et al.  CCR5 expression and B-chemokine production during placental neonatal monocyte differentiation.  Pediatric Research.  2003;53;853-858.

Professional Associations & Awards

    Association of Community Cancer Centers Innovator Award (2016)Minnesota Community Measurement Committee Member (2016 to current)American Society of Clinical Oncology Awarded NIH T32 Research Training Grant: 2010-2012


I live in Minneapolis with my wife, whose career in public health keeps me aware of the broader health care needs of the community, and two daughters. My love of running and biking helped me complete my first triathlon in 2011. I continue to play on softball and basketball teams with friends from medical school, and enjoy teaching my daughters how to field grounders and have good form on their jump shot. I am a devoted University of Minnesota Gopher basketball fan, and spend many winter nights in "The Barn."